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Showing posts from November, 2022

What is Diagnostic Pathology?

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The cause of disease is determined by morphologic and/or clinical pathology findings, as well as history, clinical signs, and ancillary test results. It is essential in all areas of pathology, both naturally occurring and experimentally induced disease. It is critical in experimental studies to distinguish between the effects of spontaneous disease and those caused by the experimental agent/test article. Diagnostic pathology is required to investigate unexpected disease or death in laboratory animal colonies or before the study is terminated. Pathology will remain important in the veterinary diagnostic laboratory for the diagnosis and prevention of spontaneous, chemically-induced disease. The value of naturally occurring chemically-induced diseases as models should not be underestimated, as these cases frequently add critical information to our understanding of the mechanisms of toxicity of these and similar chemical groups. Introduction Historically, the histologic appe...

What Exactly maxillofacial Surgery?

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  What Exactly maxillofacial Surgery? Maxillofacial surgery is a branch of dentistry . It entails procedures to correct diseases , injuries , and defects in your face, jaw, or mouth. Maxillofacial surgeons are highly trained specialists who diagnose and treat problems related to: ·          Jaw and lower face bones and tissues (maxillofacial area). ·          Your tongue's roof (palate). ·          Teeth. Oral and Maxillofacial Surgery: A dental surgeon with advanced training performs maxillofacial surgery. A wide range of maxillofacial procedures can treat diseases, repair injuries, and correct defects in your face, jaw, or mouth. As with any operation, there are risks associated with maxillofacial surgery. However, the procedures help many people reduce pain, correct deformities, and regain function. What is the purpose of maxillofacial surgery?...

Molecular pathology. The study of DNA and RNA sequencing, genes, and genetics.

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Introduction: In one sense, molecular testing has been used in surgical pathology for several decades in the context of immunohistochemistry, in which antibodies are used to detect and quantify the expression of specific proteins. However, in common parlance, molecular testing refers to testing based on the analysis of nucleic acids such as DNA and RNA. Regardless of whether the disease process is benign or malignant, most genetic testing protocols in surgical pathology are designed to detect somatic or acquired DNA mutations limited to specific cells of the disease process. The recent increase in molecular genetic tests reflects their ability to improve patient care by providing new, independent, or refined information with the potential for clinical stratification of disease subtypes, disease predispositions , prognostic categories, or treatment regimens. While this review will concentrate on the most commonly used molecular techniques in surgical pathology. It is worth not...